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International Graduate School of Neuroscience

Three images: First, a person lying inside an MRI scanner. Second, a close-up of a scientific poster with brain imaging data. Third, a person undergoing an EEG setup with electrodes being placed on their head.

Applied Methods

The Applied Methods page allows you to explore the various methods used by our members in their neuroscience research. The table below lists the method names alongside the members who apply them.

To make your search easier, use the input filter below to quickly find specific methods or members. Simply type a keyword, and the table will highlight all relevant matches across both columns.

MethodsFaculty Members
2-photon microscopyJancke
Accelerometry in humansReichert
Acute brain slicesEysel, Manahan-Vaughan
Adenoviral expression systemHeumann, Mark
Ambulatory assessmentReichert
Animal behaviorFreund, Manns, Mark, Nguyen, Pitarokoili, Rose
Animal behaviorals pardigmsFreund, Juckel, Manns, Nguyen
Animal models of brain diseaseFreund, Manns, Mark, Nguyen
Animal models of retinal/optic nerve diseasesJoachim, Pitarokoili
Animal models such as experimental autoimmune encephalomyelitis (EAE), opticospinal encephalomyelitis (OSE), and genetic knock-out modelsFaissner S, Joachim
Applied cognitive scienceWascher
Artificial brain stimulation (TMS, ICMS)Kobeleva, Nitsche
Behavioral analysis of learningElsenbruch, Icenhour, Mark, Nguyen
Behavioral studies of hippocampus-dependent learningManahan-Vaughan
Behavioral studies with PCD-controlled skinner boxes, lesion studies, pharmacology of behaviorGüntürkün, Manns
Biochemistry of the extracellular matrix and complementary receptorsFaissner A
BioinformaticsMarcus-Alic, Nguyen
BiostatisticsMarcus-Alic
Brain imaging, fluorescence in situ hybridizationManahan-Vaughan
Brain imaging, fMRI in human subjectsAxmacher, Brüne, Elsenbruch, Icenhour, Juckel, Kobeleva, Nitsche, Reichert, Schlaffke, Suchan, Wolf
Brain imaging, fMRI in rodents and birdsGüntürkün, Manahan-Vaughan
Brain imaging, wide-field calcium imagingManahan-Vaughan
Brain mappingKobeleva, Marcus-Alic, Nitsche, Wascher
Brain-computer interfaceKlaes, Kobeleva
Calcium imagingKruss, Reiner
Catecholamine imagingKruss
Cell culture models (primary murine cells, microglial or neuronal cell lines)Faissner S, Joachim, Matschke, Nguyen, Reiner
Cerebellar recordingsMark
Cerebellar slice culturesTheiss
Computational modelingCheng, Kobeleva, Nitsche, Schmidt, Wiskott
Conditioned pain modulationEnax-Krumova
Confocal microscopyEnax-Krumova, Faissner A, Kruss, Mark, Matschke, Nguyen, Pitarokoili, Reiner, Theiss
Data scienceCheng, Kobeleva, Marcus-Alic, Schmidt
Deep brain stimulationAxmacher, Nitsche
Development of bioassays for the analysis of the growth of neuritesFaissner A, Pitarokoili
Diffusion Tensor Imaging (DTI)Elsenbruch, Icenhour, Kobeleva, Schlaffke
Dissociated primary culturesFaissner A, Heumann, Matschke, Nguyen, Pitarokoili
Ecological Momentary AssessmentIcenhour, Reichert
Electroencephalogram (EEG), humanAxmacher, Kobeleva, Nitsche, Wascher, Wolf
Electroencephalogram (EEG), rodentManahan-Vaughan, Mark
Electromyography (EMG)Brüne, Kobeleva, Nitsche
Electron microscopyMatschke, Theiss
ElectrophysiologyJancke, Juckel, Klaes, Mark, Pitarokoili, Reiner, Rose
Electrophysiology of synaptic plasticityManahan-Vaughan
Electroretinography (ERG)Joachim
Enriched environmental conditionsManahan-Vaughan
Event related potentials (ERPs)Kobeleva, Nitsche, Suchan, Wascher
Evoked potentials (EP)Brüne, Enax-Krumova, Kobeleva, Nitsche, Pitarokoili
Expression of recombinant proteins in bacteria and mammalian cellsHeumann, Mark, Reiner
Eye TrackingNo members
False fluorescent neurotransmitter imagingKruss, Reiner
Flow cytometry and in cooperation scRNA sequencingFaissner S
Fluorescence microscopyMatschke
Hippocampal slice culturesReiner, Theiss
HistologyJuckel, Matschke, Nguyen
ICMS (Intracortical Micro-stimulation)Klaes
Imaging techniques (two photon microscopy, TIRF, FLIM, FRET, FRAP, BiFC)Herlitze, Reiner
ImmuncytochemistryJoachim, Juckel, Marcus-Alic, Matschke, Nguyen, Winklhofer
Immunohistochemistry and histologyEnax-Krumova, Faissner S, Freund, Güntürkün, Heumann, Joachim, Manahan-Vaughan, Manns, Marcus-Alic, Mark, Matschke, Nguyen, Pitarokoili, Tatzelt, Theiss
In vivo models of neurodegenerationJoachim, Matschke, Nguyen
In-vivo microdialysisGüntürkün
Indirect immunofluorescenceTatzelt
Intracellular measurements with sharp electrodesEysel
Intracranial EEGAxmacher, Klaes
Intraocular pressure measurements (IOP)Joachim
Ion channel pharmacologyReiner
Laser microdissectionMarcus-Alic
Learning and memory in humansElsenbruch, Icenhour, Kobeleva, Nitsche
Lesions in the brain (by laser, drugs, photothrombosis)Eysel
LipidomicsMarcus-Alic
Live-cell imagingMatschke, Reiner
Long read Next-generation sequencing (NGS)Nguyen
Machine learningKlaes, Kobeleva, Marcus-Alic, Schlaffke
Manufacturing of recombinant antibodiesHeumann
Mass spectrometryMarcus-Alic
Mathematical modelingCheng, Kobeleva, Reiner
MathematicsWiskott
Measurement of reaction timesElsenbruch, Icenhour, Nitsche, Wolf
Measurement of the peripheral conductance velocity of nerve cellsEnax-Krumova, Pitarokoili
Measurements of blood-based stress markersMarcus-Alic
Measurements of blood-based stress markers steroid hormonesMarcus-Alic
Measurements of salivary sex-steroid hormonesGüntürkün, Wolf
Measurements of salivary stress markersElsenbruch, Icenhour, Marcus-Alic, Wolf
Micro-injection techniques (proteins, DNA, etc.)Heumann, Matschke, Theiss
MicrodialysisJuckel
Mobile EEGWascher
Modelling brain activityJancke, Kobeleva
Molecular biology techniques (qPCR, Western Blot, RNA sequencing)Marcus-Alic, Matschke, Nguyen, Reiner
Molecular cloning, expression cloning, cDNA Banks, MB-techniquesFaissner A, Heumann, Marcus-Alic, Matschke, Nguyen, Reiner
Monoclonal antibodiesFaissner A
Mouse genetics (transgene expression and homologous recombination)Herlitze, Mark, Nguyen
Multi-channel electrophysiology in birdsRose
Multi-channel electrophysiology in humans, brain mapping, source localizationNitsche, Reichert
Multi-color neuronal tract tracingGüntürkün, Manns
Multimodal characterization of longitudinal patient cohorts, e.g.: clinical phenotyping, immunophenotyping, MRI analyses (cooperation)Faissner S, Kobeleva
Multivariate pattern classification analysis (MVPA)Axmacher
NanosensorsKruss
Near infrared imagingKruss
NGS data analysisNguyen, Reiner
Non-invasive brain stimulation (NIBS)Kobeleva, Nitsche
Optical coherence tomography (OCT)Joachim
Optical ImagingJancke
Optical imaging in vivoJancke
Optical recording of intrinsic signalsEysel, Jancke
OptogeneticsManns, Mark, Reiner
Organotypic slice culturesMatschke, Reiner
Pain testing in humansElsenbruch, Icenhour
Patch clamp ("blind" patch, infrared video microscopy)Eysel
Patch clamp measurements in cultured cells and slice preparationsHerlitze, Reiner
PC-based reconstruction of neurons, morphometryEysel, Güntürkün
PC-based studies of attention, learning and memory in humansNitsche, Wolf
PCRFaissner S
PCR-mutagenesis (mutations, chimaera)Heumann
PCR, RT-PCRFaissner A, Freund, Heumann, Joachim, Mark, Matschke, Nguyen, Pitarokoili, Tatzelt, Winklhofer
Pharmacological manipulation in humansEnax-Krumova, Icenhour, Nitsche, Pitarokoili, Wolf
Population coding in visual cortexJancke
Posttranslational protein modifications (phosphorylation, ubiquitination, sumoylation)Marcus-Alic, Nguyen, Winklhofer
Primary culture of dissociated neuronal and glial cellsMatschke, Nguyen, Pitarokoili, Theiss, Winklhofer
Primary cultures and cell linesHeumann, Joachim, Marcus-Alic, Mark, Matschke, Nguyen, Pitarokoili, Tatzelt, Winklhofer
Primary organ culture of retinal explantsJoachim
Programming (Matlab, Python)Jancke, Kobeleva, Schmidt
Protein analysisMarcus-Alic
Protein biochemistry, western blotsHeumann, Joachim, Marcus-Alic, Mark, Matschke, Nguyen, Pitarokoili, Reiner, Tatzelt, Winklhofer
Protein chromatographyMarcus-Alic, Reiner, Tatzelt, Winklhofer
Protein protein interactions: phage display, blot overlay, co-immunoprecipitation, pulldown, biacoreHeumann, Marcus-Alic
ProteomicsHeumann, Marcus-Alic
PsychophysicsEnax-Krumova, Klaes
Psychophysiological measurementsElsenbruch, Enax-Krumova, Icenhour, Wascher, Wolf
Psychophysiology (e.g. facial expression analysis)Juckel
Quantitative image analysis of neuroinflammatory and neurodegenerative processesPitarokoili, Schlaffke
Quantitative muscle imagingSchlaffke
Real-time optical imaging of the visualcortex using voltage-sensitive dyes in parallel with extracellular recordingsJancke
Recombinant protein expression in E. coliReiner, Tatzelt, Winklhofer
RNA-SeqNguyen
Schwann cells culturePitarokoili
Simultaneous EEG/fMRIAxmacher
Single channel recordings in vitro (inside out, outside out, cell attached)Reiner
Single-cell electrophysiology in awake, learning and anesthetized corvidsRose
Single-cell electrophysiology in awake, learning and anesthetized pigeonsGüntürkün
Single-cell labeling with BiocytinEysel
Single-cell sequencingNguyen
Single-cell studiesKruss, Nguyen
Skin biopsyEnax-Krumova, Pitarokoili
Skin conductance (electrodermal activity, EDA)Axmacher, Brüne, Icenhour
Smartphone sensing and electronic diariesReichert
Social cognitionBrüne
Source localizationNitsche
SpectroscopyIcenhour, Kruss, Reiner
StereologyManns
Stereotactic tracer injectionsGüntürkün, Manns, Mark
Stress induction in the laboratoryElsenbruch, Freund, Wolf
Structural Magnetic Resonance Imaging (sMRI)Axmacher, Icenhour, Juckel, Kobeleva, Reichert, Schlaffke
Study of nonverbal behaviorBrüne
Tactile psychophysicsEnax-Krumova
Transcranial electric stimulation (TES)Kobeleva, Nitsche
Transcranial magnetic stimulation (TMS)Brüne, Jancke, Kobeleva, Nitsche
Transfection techniquesHeumann, Mark, Matschke, Nguyen, Winklhofer
Transgenic animalsHeumann, Nguyen
Transgenic mouse modelsFreund, Jancke, Joachim, Mark, Nguyen, Pitarokoili
Video microscopyMatschke, Theiss
Virtual realityKlaes
Virus-mediated infection methodsHerlitze
Visual half-field studies in humansGüntürkün
Visual psychophysicsJancke
Whole cell-measurements in vitro, DIC MicroscopyEysel
Whole genome sequencingNguyen
Whole transcriptome sequencingNguyen
Yeast-2-Hybrid SystemHeumann

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